Tag Archives: trial

Tuberculosis Accounts for 1/3 of AIDS Deaths Worldwide

That’s why the study highlighted in this article, which demonstrates that a new vaccine reduced the rate of tuberculosis in HIV-positive people by 39%, is so important in both fighting tuberculosis and AIDS. Usually HIV-positive individuals cannot get a TB vaccine because the bacteria could re-activate in a weak immune system (for a similar article from last year, read here or here).

“Development of a new vaccine against tuberculosis is a major international health priority, especially for patients with HIV infection,” Ford von Reyn, director of the DarDar International Programs for the Section on Infectious Disease and International Health at Dartmouth Medical School, said.

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First, a vaccine in Thailand…now, one in Tanzania?

An article on Physorg.com reveals the results of a small Phase II HIV vaccine

HIV Virus

HIV Virus

trial in Tanzania: “An HIV vaccine tested in Tanzania has shown positive results in preliminary trials and may provide better protection than a promising Thai vaccine unveiled on September 24, Swedish researchers said Monday.” (Read the full article here).

One of the reasons for the increased success (up to 50% protection vs. 30% in the Thailand study) is that this vaccine included more strains of the virus. The vaccine was tested in 60 healthy Tanzanian policemen. The results will be presented at an HIV/AIDS vaccine conference in Paris on Wednesday.

So much in the news lately about HIV vaccines, and now Tanzania has been involved as well. We’ll have to watch closely over the next few months to see if this trial moves to Phase III (a larger-scale investigation) or if anything substantial comes out of the Thailand trial.

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