Tag Archives: HIV vaccine

First, a vaccine in Thailand…now, one in Tanzania?

An article on Physorg.com reveals the results of a small Phase II HIV vaccine

HIV Virus

HIV Virus

trial in Tanzania: “An HIV vaccine tested in Tanzania has shown positive results in preliminary trials and may provide better protection than a promising Thai vaccine unveiled on September 24, Swedish researchers said Monday.” (Read the full article here).

One of the reasons for the increased success (up to 50% protection vs. 30% in the Thailand study) is that this vaccine included more strains of the virus. The vaccine was tested in 60 healthy Tanzanian policemen. The results will be presented at an HIV/AIDS vaccine conference in Paris on Wednesday.

So much in the news lately about HIV vaccines, and now Tanzania has been involved as well. We’ll have to watch closely over the next few months to see if this trial moves to Phase III (a larger-scale investigation) or if anything substantial comes out of the Thailand trial.

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Optimism Surrounding HIV Vaccine Trial – Thailand

News sources everywhere are publishing optimistic headlines about the largest ever HIV vaccine trial going on right now in Thailand. But how excited should we really be? An article from UNAIDS spells out exactly what’s going on, and what it means for the world.

The study results reveal that there is a 31.2% vaccine efficacy in preventing HIV infections. While this can only be charaterized as modestly effective, these results represent new hope in HIV vaccine development. Basically, the vaccine in question, RV144, cannot be put on the market, but the data collected in Thailand this September could serve as an important foundation for the discovery of a highly effective vaccine.

The article also mentions another obstacle standing in the way of RV144; researches yet need to illucidate weather RV144 would be applicable to other regions of the world where different HIV subtypes are predominant against different host genetic backgrounds.

UNAIDS and WHO stress that until a highly effective vaccine becomes available, proven preventative messures should still be practiced.

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